2020

Grégoire Quinet, Maria Gonzalez-Santamarta, Clara Louche, Manuel S. Rodriguez. Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy. Molecules 2020, 25, 2352. DOI: 10.3390/molecules25102352.

Gonzalez-Santamarta M, Quinet G, Reyes-Garau D, Sola B, Roué G, Rodriguez MS (2020) Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma. In: Barrio R., Sutherland J., Rodriguez M. (eds) Proteostasis and Disease. Advances in Experimental Medicine and Biology, vol 1233. Springer, Cham. DOI: 10.1007/978-3-030-38266-7_6.

R Barrio, JD Sutherland, MS Rodriguez (2020). Proteostasis and Disease, from Basic Mechanisms to Clinic. Advances in Experimental Medicine and Biology (Springer International Publishing), 1233. DOI: 10.1007/978-3-030-38266-7.

AS Carvalho, H Baeta, B Costa Silva, M Carolina Strano Moraes, C Bodo, HC Beck, MS Rodriguez, M Saraswat, A Pandey, R Matthiesen (2020). Extra-cellular vesicles carry proteome of cancer hallmarks. Frontiers in bioscience (Landmark edition) 25, 398-436.

2019

S Vidal, A El Motiam, R Seoane, V Preitakaite, YH Bouzaher, S Gómez-Medina, C San Martín, D Rodríguez, M Teresa Rejas, M Baz-Martínez, R Barrio, JD Sutherland, MS Rodríguez, C Muñoz-Fontela, C Rivas (2019). Regulation of the Ebola virus VP24 protein by SUMO. Journal of virology, JVI. 01687-19.

N Dissmeyer, O Coux, MS Rodriguez, R Barrio (2019). PROTEOSTASIS: A European network to break barriers and integrate science on protein homeostasis. Trends in biochemical sciences 44 (5), 383-387.

F Lopitz Otsoa, I Zubiete-Franco, JL García-Rodríguez, M Serrano-Macia, J Simon, P Fernández-Tussy, L Barbier Torres, D Fernandez-Ramos, V Gutiérrez-de Juan, S López de Davalillo, O Carlevaris, A Beguiristain Gómez, E Villa, D Calvisi, C Martín, E Berra, P Aspichueta, N Beraza, M Varela-Rey, M Ávila, MS Rodriguez, JM Mato, I Díaz-Moreno10, A Díaz-Quintana10, T C Delgado, M L Martínez-Chantar (2019). Sumoylation/acetylation drives forward the oncogenic role of LKB1 in liver. Journal of Hepatology 70, E371-E371.

F Lopitz-Otsoa, S Lachiondo-Ortega, TC Delgado, M Azkargorta, F Elortza, MS Rodríguez,  ML Martínez-Chantar (2019). SUMO-binding entities (SUBEs) are useful tools for the enrichment, isolation, identification and characterization of the SUMO proteome from liver cancer mouse model. J Vis Exp. 2019 Nov 1;(153). DOI: 10.3791/60098.

L Mata-Cantero, MJ Chaparro, G Colmenarejo, C Cid, A Cortés, MS Rodriguez, J Martín, FJ Gamo and MG Gomez-Lorenzo. (2019) Identification of small molecules disrupting the ubiquitin proteasome system in malaria. ACS Infectious Diseases. Dec 13;5(12):2105-2117. DOI: 10.1021/acsinfecdis.9b00216

M Mattern, J Sutherland, K Kadimisetty, R Barrio, MS Rodriguez (2019). Using Ubiquitin Binders to Decipher the Ubiquitin Code. Trends in biochemical sciences.

I Zubiete-Franco, JL García-Rodríguez, F Lopitz-Otsoa, M Serrano-Macia, J Simon, P Fernández-Tussy, L Barbier-Torres, D Fernández-Ramos, V Gutiérrez-de-Juan, S López de Davalillo, O Carlevaris, A Beguiristain Gómez, E Villa, D Calvisi, C Martín, E Berra, P Aspichueta, N Beraza, M Varela-Rey, M Ávila, MS Rodríguez, JM Mato, I Díaz-Moreno, A Díaz-Quintana, TC Delgado, ML Martínez-Chantar (2019). SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer. EBioMedicine 40, 406-421.

2018

P Gomez-Bougie, S Maiga, B Tessoulin, J Bourcier, A Bonnet, MS Rodriguez, S Le Gouill, C Touzeau, P Moreau, C Pellat-Deceunynck, M Amiot (2018). BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment. Blood 132 (25), 2656-2669.

A Gärtner, K Wagner, S Hölper, K Kunz, MS Rodriguez, S Müller (2018). Acetylation of SUMO2 at lysine 11 favors the formation of non‐canonical SUMO chains. EMBO reports 19 (11).

O Domínguez-Acosta, L Vega, E Estrada-Muñiz, MS Rodríguez, FJ Gonzalez, G Elizondo (2018). Activation of aryl hydrocarbon receptor regulates the LPS/IFNγ-induced inflammatory response by inducing ubiquitin-proteosomal and lysosomal degradation of RelA/p65. Biochemical pharmacology 155, 141-149.

A El Motiam, S Vidal, CF de la Cruz-Herrera, S Da Silva-Álvarez, M Baz-Martínez, R Seoane, A Vidal, MS Rodríguez, DP Xirodimas, AS Carvalho, H Christian Beck, R Matthiesen, M Collado, C Rivas (2018). Interplay between SUMOylation and NEDDylation regulates RPL11 localization and function. The FASEB Journal 33 (1), 643-651.

A Azpilikueta, E Bolanos, V Lang, S Labiano, MA Aznar, I Etxeberria, A Teijeira, M E Rodriguez-Ruiz, JL Perez-Gracia, M Jure-Kunkel, JM Zapata, MS Rodriguez, I Melero (2018). Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4–1BB). OncoImmunology 7 (1), e1368605.

CM Maghames, S Lobato-Gil, A Perrin, H Trauchessec, MS Rodriguez, S Urbach, P Marin, DP Xirodimas (2018). NEDDylation promotes nuclear protein aggregation and protects the ubiquitin proteasome system upon proteotoxic stress. Nature communications 9.

 

2017

V Lang, F Aillet, W Xolalpa, S Serna, L Ceccato, RG Lopez-Reyes, M Paz Lopez-Mato, R Januchowski, NC Reichardt, MS Rodriguez (2017). Analysis of defective protein ubiquitylation associated to adriamycin resistant cells. Cell Cycle 16 (24), 2337-2344.

F Carlos, M Baz-Martínez, A El Motiam, S Vidal, M Collado, A Vidal, MS Rodríguez, M Esteban, C Rivas (2017). Phosphorylable tyrosine residue 162 in the double-stranded RNA-dependent kinase PKR modulates its interaction with SUMO. Scientific reports 7 (1), 14055.

S Wiechmann, A Gärtner, A Kniss, A Stengl, C Behrends, V V Rogov, MS Rodriguez, V Dötsch, S Müller, A Ernst (2017). Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation. Journal of Biological Chemistry 292 (37), 15340-15351.

L Pirone, W Xolalpa, J O Sigurðsson, J Ramirez, C Pérez, M González, A Ruiz De Sabando, F Elortza, MS Rodriguez, U Mayor, J V Olsen, R Barrio, J D Sutherland (2017). A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation. Scientific reports 7, 40756.

AS Carvalho, MS Rodriguez, R Matthiesen (2017). Red Blood Cells in Clinical Proteomics. Serum/Plasma Proteomics, 173-181.

2016

R López de Maturana, V Lang, A Zubiarrain, A Sousa, N Vázquez, A Gorostidi, J Águila, A López de Munain, MS Rodríguez, RSánchez-Pernaute. Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons. Journal of neuroinflammation 13 (1), 295.

M Baz-Martínez, A El Motiam, P Ruibal, G N Condezo, F Carlos, V Lang, M Collado, C San Martín, MS Rodríguez, CMuñoz-Fontela, C Rivas. Regulation of Ebola virus VP40 matrix protein by SUMO. Scientific reports 6, 37258.

E Da Silva-Ferrada, TM Ribeiro-Rodrigues, MS Rodríguez, H Girão (2016). Proteostasis and SUMO in the heart. The international journal of biochemistry & cell biology 79, 443-450.

S Serna, W Xolalpa, V Lang, F Aillet, P England, N Reichardt, MS Rodriguez (2016). Efficient monitoring of protein ubiquitylation levels using TUBE s‐based microarrays. FEBS letters 590 (16), 2748-2756.

CF De la Cruz-Herrera, M Baz-Martínez, V Lang, A El Motiam, J Barbazán, R Couceiro, M Abal, A Vidal, M Esteban, C Muñoz-Fontela, A Nieto, MS Rodriguez, M Collado, C Rivas (2016). Conjugation of SUMO to p85 leads to a novel mechanism of PI3K regulation. Oncogene 35 (22), 2873.

L Mata-Cantero, M Azkargorta, F Aillet, W Xolalpa, M J LaFuente, F Elortza, AS Carvalho, J Martin-Plaza, R Matthiesen, MS Rodriguez (2016). New insights into host-parasite ubiquitin proteome dynamics in P. falciparum infected red blood cells using a TUBEs-MS approach. Journal of proteomics 139, 45-59.

AS Carvalho, MS Rodríguez, R Matthiesen (2016). Review and literature mining on proteostasis factors and cancer. Proteostasis, 71-84.

W Xolalpa, L Mata-Cantero, F Aillet, MS Rodriguez (2016). Isolation of the ubiquitin-proteome from tumor cell lines and primary cells using TUBEs. Proteostasis, 161-175.

M Azkargorta, I Escobes, F Elortza, R Matthiesen, MS Rodriguez (2016). TUBEs-mass spectrometry for identification and analysis of the ubiquitin-proteome. Proteostasis, 177-192.

MJ Matunis, MS Rodriguez (2016). Concepts and methodologies to study protein SUMOylation: an overview. SUMO, 3-22.

V Lang, E Da Silva-Ferrada, R Barrio, JD Sutherland, MS Rodriguez (2016). Using biotinylated SUMO-traps to analyze SUMOylated proteins. SUMO, 109-121.

W Xolalpa, MS Rodriguez, P England (2016). Real-time surface plasmon resonance (SPR) for the analysis of interactions between SUMO traps and mono-or polySUMO moieties. SUMO, 99-107.