2022
Grégoire Quinet, Wendy Xolalpa, Diana Reyes-Garau, Núria Profitós-Pelejà, Mikel Azkargorta, Laurie Ceccato, Maria Gonzalez-Santamarta, Maria Marsal, Jordi Andilla, Fabienne Aillet, Francesc Bosch, Felix Elortza, Pablo Loza-Alvarez, Brigitte Sola, Olivier Coux, Rune Matthiesen, Gaël Roué, and Manuel S. Rodriguez (2022). « Constitutive Activation of p62/Sequestosome-1-Mediated Proteaphagy Regulates Proteolysis and Impairs Cell Death in Bortezomib-Resistant Mantle Cell Lymphoma » Cancers 14, no. 4: 923. DOI: 10.3390/cancers14040923.
2021
Maria Gonzalez-Santamarta, Corentin Bouvier, Manuel S. Rodriguez and Wendy Xolalpa (2021). Ubiquitin-chains dynamics and its role regulating crucial cellular processes. Seminars in Cell & Developmental Biology, ISSN 1084-9521. DOI : 10.1016/j.semcdb.2021.11.023
Sofia Lobato-Gil, Jan B Heidelberger, Chantal Maghames, Aymeric Bailly, Lorene Brunello, Manuel S Rodriguez, Petra Beli, Dimitris P Xirodimas. Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation. Cell Reports 34 (3), 108635, 2021. DOI: 10.1016/j.celrep.2020.108635.
2020
Sofia Lobato-Gil, Jan B Heidelberger, Chantal Maghames, Aymeric Bailly, Lorene Brunello, Manuel S Rodriguez, Petra Beli, Dimitris P Xirodimas. Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation. Cell Reports 34 (3), 108635, 2021. DOI: 10.1016/j.celrep.2020.108635.
Rosa G. Lopez‐Reyes, Grégoire Quinet, Maria Gonzalez‐Santamarta, Clément Larrue, Jean‐Emmanuel Sarry, Manuel S. Rodriguez. Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia. FEBS Open Bio (2020). DOI: 10.1002/2211-5463.12950.
Grégoire Quinet, Maria Gonzalez-Santamarta, Clara Louche, Manuel S. Rodriguez. Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy. Molecules 2020, 25, 2352. DOI: 10.3390/molecules25102352.
Gonzalez-Santamarta M, Quinet G, Reyes-Garau D, Sola B, Roué G, Rodriguez MS (2020) Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma. In: Barrio R., Sutherland J., Rodriguez M. (eds) Proteostasis and Disease. Advances in Experimental Medicine and Biology, vol 1233. Springer, Cham. DOI: 10.1007/978-3-030-38266-7_6.
R Barrio, JD Sutherland, MS Rodriguez (2020). Proteostasis and Disease, from Basic Mechanisms to Clinic. Advances in Experimental Medicine and Biology (Springer International Publishing), 1233. DOI: 10.1007/978-3-030-38266-7.
AS Carvalho, H Baeta, B Costa Silva, M Carolina Strano Moraes, C Bodo, HC Beck, MS Rodriguez, M Saraswat, A Pandey, R Matthiesen (2020). Extra-cellular vesicles carry proteome of cancer hallmarks. Frontiers in bioscience (Landmark edition) 25, 398-436.
2019
S Vidal, A El Motiam, R Seoane, V Preitakaite, YH Bouzaher, S Gómez-Medina, C San Martín, D Rodríguez, M Teresa Rejas, M Baz-Martínez, R Barrio, JD Sutherland, MS Rodríguez, C Muñoz-Fontela, C Rivas (2019). Regulation of the Ebola virus VP24 protein by SUMO. Journal of virology, JVI. 01687-19.
N Dissmeyer, O Coux, MS Rodriguez, R Barrio (2019). PROTEOSTASIS: A European network to break barriers and integrate science on protein homeostasis. Trends in biochemical sciences 44 (5), 383-387.
F Lopitz Otsoa, I Zubiete-Franco, JL García-Rodríguez, M Serrano-Macia, J Simon, P Fernández-Tussy, L Barbier Torres, D Fernandez-Ramos, V Gutiérrez-de Juan, S López de Davalillo, O Carlevaris, A Beguiristain Gómez, E Villa, D Calvisi, C Martín, E Berra, P Aspichueta, N Beraza, M Varela-Rey, M Ávila, MS Rodriguez, JM Mato, I Díaz-Moreno10, A Díaz-Quintana10, T C Delgado, M L Martínez-Chantar (2019). Sumoylation/acetylation drives forward the oncogenic role of LKB1 in liver. Journal of Hepatology 70, E371-E371.
F Lopitz-Otsoa, S Lachiondo-Ortega, TC Delgado, M Azkargorta, F Elortza, MS Rodríguez, ML Martínez-Chantar (2019). SUMO-binding entities (SUBEs) are useful tools for the enrichment, isolation, identification and characterization of the SUMO proteome from liver cancer mouse model. J Vis Exp. 2019 Nov 1;(153). DOI: 10.3791/60098.
L Mata-Cantero, MJ Chaparro, G Colmenarejo, C Cid, A Cortés, MS Rodriguez, J Martín, FJ Gamo and MG Gomez-Lorenzo. (2019) Identification of small molecules disrupting the ubiquitin proteasome system in malaria. ACS Infectious Diseases. Dec 13;5(12):2105-2117. DOI: 10.1021/acsinfecdis.9b00216
M Mattern, J Sutherland, K Kadimisetty, R Barrio, MS Rodriguez (2019). Using Ubiquitin Binders to Decipher the Ubiquitin Code. Trends in biochemical sciences.
I Zubiete-Franco, JL García-Rodríguez, F Lopitz-Otsoa, M Serrano-Macia, J Simon, P Fernández-Tussy, L Barbier-Torres, D Fernández-Ramos, V Gutiérrez-de-Juan, S López de Davalillo, O Carlevaris, A Beguiristain Gómez, E Villa, D Calvisi, C Martín, E Berra, P Aspichueta, N Beraza, M Varela-Rey, M Ávila, MS Rodríguez, JM Mato, I Díaz-Moreno, A Díaz-Quintana, TC Delgado, ML Martínez-Chantar (2019). SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer. EBioMedicine 40, 406-421.
2018
P Gomez-Bougie, S Maiga, B Tessoulin, J Bourcier, A Bonnet, MS Rodriguez, S Le Gouill, C Touzeau, P Moreau, C Pellat-Deceunynck, M Amiot (2018). BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment. Blood 132 (25), 2656-2669.
A Gärtner, K Wagner, S Hölper, K Kunz, MS Rodriguez, S Müller (2018). Acetylation of SUMO2 at lysine 11 favors the formation of non‐canonical SUMO chains. EMBO reports 19 (11).
O Domínguez-Acosta, L Vega, E Estrada-Muñiz, MS Rodríguez, FJ Gonzalez, G Elizondo (2018). Activation of aryl hydrocarbon receptor regulates the LPS/IFNγ-induced inflammatory response by inducing ubiquitin-proteosomal and lysosomal degradation of RelA/p65. Biochemical pharmacology 155, 141-149.
A El Motiam, S Vidal, CF de la Cruz-Herrera, S Da Silva-Álvarez, M Baz-Martínez, R Seoane, A Vidal, MS Rodríguez, DP Xirodimas, AS Carvalho, H Christian Beck, R Matthiesen, M Collado, C Rivas (2018). Interplay between SUMOylation and NEDDylation regulates RPL11 localization and function. The FASEB Journal 33 (1), 643-651.
A Azpilikueta, E Bolanos, V Lang, S Labiano, MA Aznar, I Etxeberria, A Teijeira, M E Rodriguez-Ruiz, JL Perez-Gracia, M Jure-Kunkel, JM Zapata, MS Rodriguez, I Melero (2018). Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4–1BB). OncoImmunology 7 (1), e1368605.
CM Maghames, S Lobato-Gil, A Perrin, H Trauchessec, MS Rodriguez, S Urbach, P Marin, DP Xirodimas (2018). NEDDylation promotes nuclear protein aggregation and protects the ubiquitin proteasome system upon proteotoxic stress. Nature communications 9.
2017
V Lang, F Aillet, W Xolalpa, S Serna, L Ceccato, RG Lopez-Reyes, M Paz Lopez-Mato, R Januchowski, NC Reichardt, MS Rodriguez (2017). Analysis of defective protein ubiquitylation associated to adriamycin resistant cells. Cell Cycle 16 (24), 2337-2344.
F Carlos, M Baz-Martínez, A El Motiam, S Vidal, M Collado, A Vidal, MS Rodríguez, M Esteban, C Rivas (2017). Phosphorylable tyrosine residue 162 in the double-stranded RNA-dependent kinase PKR modulates its interaction with SUMO. Scientific reports 7 (1), 14055.
S Wiechmann, A Gärtner, A Kniss, A Stengl, C Behrends, V V Rogov, MS Rodriguez, V Dötsch, S Müller, A Ernst (2017). Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation. Journal of Biological Chemistry 292 (37), 15340-15351.
L Pirone, W Xolalpa, J O Sigurðsson, J Ramirez, C Pérez, M González, A Ruiz De Sabando, F Elortza, MS Rodriguez, U Mayor, J V Olsen, R Barrio, J D Sutherland (2017). A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation. Scientific reports 7, 40756.
AS Carvalho, MS Rodriguez, R Matthiesen (2017). Red Blood Cells in Clinical Proteomics. Serum/Plasma Proteomics, 173-181.
2016
R López de Maturana, V Lang, A Zubiarrain, A Sousa, N Vázquez, A Gorostidi, J Águila, A López de Munain, MS Rodríguez, RSánchez-Pernaute. Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons. Journal of neuroinflammation 13 (1), 295.
M Baz-Martínez, A El Motiam, P Ruibal, G N Condezo, F Carlos, V Lang, M Collado, C San Martín, MS Rodríguez, CMuñoz-Fontela, C Rivas. Regulation of Ebola virus VP40 matrix protein by SUMO. Scientific reports 6, 37258.
E Da Silva-Ferrada, TM Ribeiro-Rodrigues, MS Rodríguez, H Girão (2016). Proteostasis and SUMO in the heart. The international journal of biochemistry & cell biology 79, 443-450.
S Serna, W Xolalpa, V Lang, F Aillet, P England, N Reichardt, MS Rodriguez (2016). Efficient monitoring of protein ubiquitylation levels using TUBE s‐based microarrays. FEBS letters 590 (16), 2748-2756.
CF De la Cruz-Herrera, M Baz-Martínez, V Lang, A El Motiam, J Barbazán, R Couceiro, M Abal, A Vidal, M Esteban, C Muñoz-Fontela, A Nieto, MS Rodriguez, M Collado, C Rivas (2016). Conjugation of SUMO to p85 leads to a novel mechanism of PI3K regulation. Oncogene 35 (22), 2873.
L Mata-Cantero, M Azkargorta, F Aillet, W Xolalpa, M J LaFuente, F Elortza, AS Carvalho, J Martin-Plaza, R Matthiesen, MS Rodriguez (2016). New insights into host-parasite ubiquitin proteome dynamics in P. falciparum infected red blood cells using a TUBEs-MS approach. Journal of proteomics 139, 45-59.
AS Carvalho, MS Rodríguez, R Matthiesen (2016). Review and literature mining on proteostasis factors and cancer. Proteostasis, 71-84.
W Xolalpa, L Mata-Cantero, F Aillet, MS Rodriguez (2016). Isolation of the ubiquitin-proteome from tumor cell lines and primary cells using TUBEs. Proteostasis, 161-175.
M Azkargorta, I Escobes, F Elortza, R Matthiesen, MS Rodriguez (2016). TUBEs-mass spectrometry for identification and analysis of the ubiquitin-proteome. Proteostasis, 177-192.
MJ Matunis, MS Rodriguez (2016). Concepts and methodologies to study protein SUMOylation: an overview. SUMO, 3-22.
V Lang, E Da Silva-Ferrada, R Barrio, JD Sutherland, MS Rodriguez (2016). Using biotinylated SUMO-traps to analyze SUMOylated proteins. SUMO, 109-121.
W Xolalpa, MS Rodriguez, P England (2016). Real-time surface plasmon resonance (SPR) for the analysis of interactions between SUMO traps and mono-or polySUMO moieties. SUMO, 99-107.